5 Freeway reopens after big-rig accident

By Nicole Santa Cruz

January 15, 2013, 8:08 a.m.

All lanes of the 5 Freeway near Elysian Park were reopened Tuesday morning after a big rig hit the center divider and caught fire, backing up traffic for miles during the early commute.

Authorities reopened the freeway shortly after 7:30 a.m., said Officer Monica Posada of the California Highway Patrol.

Traffic delays are still expected in the area around Fletcher Drive on the southbound side and Stadium Way on the northbound side.

The closure was prompted at 3:16 a.m. when the big rig crashed into the center divider. No injuries were reported in the accident.

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Myspace Relaunches With New Justin Timberlake Single 'Suit & Tie'

By Eliot Van Buskirk, Evolver.fm

Some artists send out a press release when they have a new single. Justin Timberlake invests in an old social network, helps relaunch it, and makes his new track the first thing that loads up on the homepage.

After months of private beta previews, the new Myspace emerged to the public today, with a fresh redesign and a new focus on helping artists post music to share with fans. The first thing you’ll see, in multiple places, is Timberlake’s first new single since 2006′s FutureSex/LoveSounds, “Suit & Tie, FT Jay-Z,” which streams on Myspace for free with an iTunes purchase link below it.

By promoting his new single with the launch of an entire social network, Timberlake appears to be sending a message to other artists about what the new Myspace is for: posting music for free, and trying to upsell it to downloads. The new site makes it super-easy for any user to repost any song they find from their own profile, which Timberlake no doubt hopes will become something people do quite a bit.

In other words, it’s back to the original vision of MySpace, which it supplanted MP3.com as the default place for artists to upload their music, and became, for a while there, the best place to research and hear any band. (Remember, this was before YouTube became a licensed music service, and way before anything like the free version of Spotify).

If you remember your old password and have access to your old email address, you can log in with those or a new email address — or just use Twitter or Facebook credentials, a clear sign that the new Myspace envisions itself not as a competitor to those two services, but rather as a new music-focused social network.

After you get past a couple of screens featuring Timberlake’s own jam, you’ll see plenty of other artists in the Discover section, which includes trending items (artists, users, videos, and so on), as well as a prominent music-specific section (high rotation, new albums, artists, and recommended). The new Myspace also has a streaming radio function, in case you get tired of looking for stuff, with the ability to play artist or genre stations. Finally, a mixes section lets people share playlists.

The new Myspace is everything the old one wasn’t towards the end: Simple, non-confusing, modern, clean, and focused. It looks great, as noted in October, when the new version emerged in beta.

Will anyone care? If they like Justin Timberlake, they will care for today, at least. Myspace appears to have all the tools it needs to become a player in the free, promotional music space, but of course, a social network is nothing without people, and there’s obviously no way to tell whether they will come to rely on Myspace to discover music and find out more about artists. As crazy as it would have seemed a few years ago, when Myspace was floundering, it does appear to stand a chance, especially given this initial boost from Timberlake’s star power.

Justin Timberlake played Sean Parker in The Social Network. Does he think he is Sean Parker now?

When Wired interviewed Justin Timberlake in 2010 at the launch of his fashion brand, he said, “We get creative with a lot of different brands but they’re so specific to each other. I don’t cross-promote anything of mine unless it genuinely feels organic. For instance, I have one of my bands playing the music for the fashion show, but that makes sense. I wouldn’t do something that was pushing something that wasn’t organic.”

In this case, he appears to be playing by those rules.

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Poet Sharon Olds wins T.S. Eliot award

LONDON (Reuters) – American poet Sharon Olds won the T.S. Eliot Prize for Poetry on Monday for “Stag’s Leap”, a critically acclaimed collection that traces the end of her marriage 15 years ago.

The annual award, celebrating its 20th anniversary, goes to what a panel of poets decides is the best collection of verse published in the United Kingdom and Ireland each year, and is considered to be one of the world’s top poetry prizes.

Stag’s Leap, published in Britain by Jonathan Cape, was chosen from a record 131 submissions and a shortlist of 10.

“From over 130 collections, we were particularly impressed by the strong presence of women on the list and were unanimous in awarding the 2012 T.S. Eliot Prize to Sharon Olds‘ Stag’s Leap,” said Carol Ann Duffy, chair of the judges.

Duffy, also Britain’s poet laureate since 2009, called the work “a tremendous book of grace and gallantry which crowns the career of a world-class poet.”

Olds wins a cheque for 15,000 pounds ($ 24,000) for the prize, which is administered by the Poetry Book Society and supported by the estate of leading 20th century poet T.S. Eliot whose works include “The Waste Land”.

When her marriage ended, Olds, now 70, promised her children she would not write about the divorce for 10 years. In fact, it took her 15 years to get around to publishing a collection which some critics said was her best yet.

“Olds, who has always had a gift for describing intimacy, has, in a sense, had these poems thrown at her by life and allowed them to take root: they are stunning – the best of a formidable career,” wrote Kate Kellaway in The Observer.

The critic added that the collection was surprisingly kind considering its subject matter.

In “Unspeakable”, from Stag’s Leap, Olds writes:

“He shows no anger,/I show no anger but in flashes of humor/all is courtesy and horror. And after/the first minute, when I say, Is this about/her, and he says, No, it’s about/you, we do not speak of her.”

Olds was born in San Francisco in 1942 and her first collection of poems, “Satan Says” (1980), received the inaugural San Francisco Poetry Center Award.

She went on to win a string of other prizes and currently teaches creative writing at New York University.

(Reporting by Mike Collett-White, editing by Paul Casciato)

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Well: For DTaP Vaccine, Thigh May Be Better Injection Site Than Arm

Children are less likely to develop bad reactions to the DTaP vaccine, a routine immunization shot that protects against diphtheria, tetanus and pertussis, or whooping cough, if they get it in their thigh instead of in their arm, a new study shows.

The research looked at more than a million children who were given injections of the vaccine. In many cases it causes some degree of redness or swelling around the injection site, which typically goes away after a day. But in rare instances a child can develop a more pronounced reaction, like severe pain or a swollen limb, that may require medical attention.

In the new study, which was published in the journal Pediatrics, researchers found that children between the ages of 1 and 3 who were given the DTaP vaccine in their thigh instead of in their upper arm were around half as likely to have a local reaction that warranted a visit to a doctor, nurse or emergency room. Previous studies of children who received the vaccine between the ages of 4 and 6 found that they, too, had a lower likelihood of developing a local reaction requiring medical attention if they got the shot in their thigh instead of in their arm.

Why the vaccine would be less harsh on the thigh than the arm is not known for certain. But one possibility is simply that in children at that age, the thigh muscle is much larger than the deltoid, the muscle in the upper arm where shots are typically administered. If any inflammation ensues, it has more room to diffuse in the thigh, said Dr. Lisa A. Jackson, the lead author of the study and a senior investigator at the Group Health Research Institute in Seattle.

“In little kids the upper arm is very tiny,” she said. “You’re injecting the same volume of vaccine in the upper arm as in the thigh, which is a larger area. I think it’s just that it’s a larger muscle mass.”

The benefits, however, may not extend to other immunizations. The study, for example, also looked at shots for influenza and hepatitis A, and in those cases there was no meaningful difference between vaccinating in the arm or thigh for either toddlers or children ages 3 to 6.

In many cases, doctors choose where to administer a shot according to their own preference. But in the case of DTaP, at least, it makes more sense in general to give the shot in the thigh, Dr. Jackson said.

“Unless there’s a compelling reason not to, I would say veer toward giving the DTaP vaccine in the leg,” she said. “There’s less chance of a concerning reaction if you give it in the thigh versus the arm. So that should be the normal practice.”

Dr. Jackson stressed, however, that the absolute risk of a child having a reaction severe enough to warrant medical attention is still quite small, regardless of whether the shot is given in the arm or leg. The study found that it occurred in less than 1 percent of vaccinated children over all.

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Roche Hires Dr. John Reed to Lead Research Operations

The Swiss pharmaceutical giant Roche is turning to a prolific American academic scientist to revitalize its lagging research operations.

Dr. John C. Reed, the chief executive of the Sanford-Burnham Medical Research Institute in San Diego, will become head of Roche’s pharmaceutical research and early development group in April, the company announced Tuesday.

Dr. Reed, 54, has spent 21 years at Sanford-Burnham, formerly known as the Burnham Institute, the last 11 as chief executive.

During his tenure as chief executive, the institute grew rapidly, opened a new research site in Florida, and broadened its role from basic research to also doing drug discovery, in some cases in collaborations with pharmaceutical companies. It also received its largest donation ever, $50 million, from the credit card industry executive T. Denny Sanford, which led the institute to change its name.

Dr. Reed, 54, who holds both a medical degree and a Ph.D., is the author of more than 800 scientific papers, many dealing with why cancer cells do not commit suicide as errant cells are supposed to do. A triathlete, Dr. Reed used to get to his office around 3:30 a.m. each day, though now, with better computers, he works at home in the early hours.

“With his broad scientific and medical background, he is ideally positioned to drive Roche’s strategy of translating a better understanding of disease mechanisms into promising therapeutics,” Severin Schwan, the chief of Roche, said in a statement.

It is not unprecedented for drug companies to tap academic scientists to run research. Sanofi’s research and development is now run by Elias Zerhouni, the former director of the National Institutes of Health and professor at Johns Hopkins. Mark Fishman, a cardiologist at Harvard, was recruited to run research at Novartis, and Peter S. Kim, who heads research at Merck, was previously a biology professor at the Massachusetts Institute of Technology.

Dr. Reed, who has been on biotechnology company boards but never had a full-time corporate job, said in an interview that he was joining Roche to “have an opportunity to contribute on a larger stage, so to speak.”

At Roche he will oversee not only research but also early- and middle-stage clinical trials, something Sanford-Burnham does not do. He will supervise about 2,000 people with an annual budget in the billions, while Sanford-Burnham has about 1,200 people and a budget of around $175 million.

Dr. Reed, who will move to Basel, where Roche is based, said it was too early to discuss his agenda at Roche, other than to make its research more collaborative.

The operation Dr. Reed will run, called Pharma Research and Early Development, or pRED, does not include Genentech, the California biotechnology company that Roche fully acquired in 2009. In an effort to preserve the culture at Genentech, Roche left it autonomous, forming a group it calls gRED.

Recently, gRED has been eclipsing pRED. Roche’s three best-selling drugs, the cancer medicines Rituxan, Herceptin and Avastin, were developed at Genentech. So have some of its most attractive experimental drugs, including T-DM1, a breast cancer drug that could win regulatory approval early this year.

The organization Dr. Reed will run, by contrast, has had its share of problems in recent years. Several hundred researchers were cut in a corporate reorganization. And last year Roche discontinued development of a heart drug after it failed to work in a late-stage clinical trial.

The troubles contributed to Roche’s decision in June to shut its campus in Nutley, N.J., the birthplace of valium. At that time, Jean-Jacques Garaud, head of the Roche unit that Dr. Reed will run, left the company and was replaced on an interim basis by Mike Burgess. Roche said Tuesday that Mr. Burgess would now also leave the company.

Sanford-Burnham said that Dr. Kristiina Vuori, its president and head of its cancer center, would take over as chief executive on an interim basis. Dr. Vuori, who is originally from Finland, has worked closely with Dr. Reed.

M. Wainwright Fishburn Jr., the chairman of Sanford-Burnham, said it was “bittersweet” to see Dr. Reed leave. While the institute will lose a very successful leader, he said, the move could advance the institute’s efforts to get drug discovery work from pharmaceutical companies.

“We have one of our own in one of the most influential positions around,” he said.

This article has been revised to reflect the following correction:

Correction: January 15, 2013

A headline with an earlier version of this article misspelled the name of the drug maker. It is Roche, not Roches.

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An Anaheim woman demands respect for her neighborhood

Yesenia Rojas, vibrant in her purple shawl, sang with a voice so powerful it rose above the rest of the procession as they shuffled down the damp Anaheim sidewalk.

"Era mexicana. Era mexicana," they sang with a statue of Our Lady of Guadalupe hoisted high, candlelight and street lamps illuminating their way. "Madrecita de los mexicanos."

The singsong serenade lauds the patroness, the mother of all Mexicans.

On this drizzly evening, Rojas led the group down Anna Drive, where she and her family have made their home.

In a city often defined by Disneyland and elegant sports venues, this street of working-class Latino immigrants has become an avatar of a lesser-known, voiceless Anaheim, one riddled with poverty and gangs.

When police shot and killed a 25-year-old alleged gang member who lived on Anna Drive, it stoked what had been a growing fire in the city. It was the latest in a spate of police shootings last year, which inflamed anger with law enforcement into a larger sense of resentment over ethnic and class fissures that divide Orange County's largest city.

Unrest — amplified by Occupy-connected protesters from outside the city — gripped Anaheim for days after the July shooting, followed by weeks of heated City Council meetings.

The wave of protesters demanding change has washed away, but Rojas has emerged in its wake. The 35-year-old mother of six, with short, wavy dark hair and a small frame that belies her force of will, has taken it upon herself to become the voice of Anna Drive.

Her family lives in a one-bedroom apartment just yards from where Manuel Diaz was shot that summer day. Rojas' 14-year-old daughter saw Diaz's body and has been traumatized since. Her mother can't let that go.

"I thought about leaving, and so did my husband, because of the children," she said. "But I said no. Because, first of all, we don't need to fear anyone, not even the police. The biggest thing right now is to stay on our feet and make things happen as a community. If we all leave, things won't change. They'll keep trampling us and humiliating us."

Rojas has a vision for her community that would seem bold if her wishes weren't so simple: She imagines playgrounds and community centers and political representation. But most of all, she sees respect for Anna Drive.

She balances two jobs, but she makes time for her community. She bends the ears of politicians. She organizes rallies encouraging her neighbors to register to vote and head to the polls. She plans events that she hopes will draw together a community that has grown accustomed to seeing itself as the backdrop of news cameras trying to highlight the city's ills.

And on this night, dozens gathered to pray a rosario in the tight courtyard outside her apartment, where the statue of the Virgin rested on an altar of roses and carnations.

As sirens echoed in the distance, the crowd stayed late into the night. They sang, they danced, they sipped cinnamon-spiced coffee.

And they prayed, petitioning the Virgin Mother for peace and for guidance.

"This is the community," Rojas said. "These are the people of Anna Drive."

::

Anna Drive, a collection of squat, modest apartment buildings, horseshoes off of a busy thoroughfare. On any given day, it pulses with life: children whipping down the sidewalk on scooters and skateboards, older boys tussling with one another and nanas and tatas watching it all unfold from chairs in their frontyards.

The street is clogged with cars and the vending truck that always seems to be parked along the same slice of curb, hawking snacks, produce and spices to the families who live on this stretch of tidy apartments and small, fenced-in lawns.

Rojas came to Anna Drive about a year ago, moving her family into the tight but comfortable apartment, its walls lined with family photographs. She was born in the Mexican state of Guanajuato, but she has lived much of her life in the flatlands of Anaheim. Her mother has lived in the same apartment, just a few blocks away, for decades.

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CAD Designer Transforms <em>Halo</em> Chief Into Bobble Heads

Master Chief from the Halo series is one of the most fearsome computer-generated characters of all time, as well as a popular product license for everything from action figures to desk toys. When Funko licensed characters from the iconic Xbox franchise to make bobble heads, they recruited CAD/3-D printer artist Khurram Alavi to handle the mini-makeover.

Alavi grew up on a steady diet of animated shows and videogames from the ’80s and ’90s and dreamed of becoming a comic book artist. After earning a design degree in Pakistan, he joined a local animation firm where he discovered ZBrush, a powerful CAD package developed for the entertainment industry. “The world of 3-D just opened up to me,” says Alavi. “It was as if I was sketching, but with actual clay. I started using the software and began entering online contests. I won a few and managed to get some gigs with Marvel- and Sega-based characters.”

He went on to model characters from Star Wars and completed projects for Valve Software, but the Halo bobble head project proved to be more difficult to manage than an evil mutant or fearsome Street Fighter because it had to be cute. “Trust me when I say this — cute and small is not as simple as you may think,” says Alavi. “In fact, it is very challenging as the simplified forms and curvature need to be perfect in every way. I’ve spent days on the simplest of designs just to get the curves right.”

The character and a rough idea for a pose are all Alavi had to work with. “Funko sends over rough ideas for the pose and that’s about it.” says Alavi. “It’s my job to translate it and make it work in 3-D.” Funko also provided the original 3-D models used in Halo 4, but they were of limited use because of the differing requirements in videogames and design for manufacturing. “I could barely use those models as they were made for the game, but they did help speed up with sculpting process.” he says. “I was able to nail the costume elements and details very quickly.”

The model had to capture Masture Chief’s unique look, but was also required to be manufacturable at a low cost, which required great artistry from Alavi. “When you bring more than 40 individual costume elements into the mix, it gets far more complicated,” he says. “Then to make sure that the parts are thick and detailed enough and will be produced properly is another challenge within itself.”

In order to test his models, Alavi turned to 3-D printers and worked with a firm in Hong Kong called Ownage Manufacturing, which specializes in 3-D printing complex ZBrush models. “The approval process is usually very painful, with a lot of back and forth between myself and the licensor,” says Alavi. “They want their designs to be as accurate to the source material as possible, and rightly so. A one-week job can go up to two months sometimes in the collectibles business.”

Fortunately for Alavi, working in pixels has huge benefits over modeling with plasticine clay. “The digital sculpt is very fast in this respect as we can make changes very on the fly and takes less time when compared to making changes to a physical real world sculpture.”

CAD software and 3-D printers have essentially become a “reset” button for the real world.

Photos: Khurram Alavi

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Justin Timberlake releases ‘Suit & Tie,’ first single in 5 years

LOS ANGELES (Reuters) – Pop star Justin Timberlake unveiled on Sunday his first single in more than five years, “Suit & Tie,” featuring rapper Jay Z and producer Timbaland and said a new album would be released later in 2013.

Timberlake, 31 and newly married to actress Jessica Biel, had teased his fans last week with a cryptic tweet saying “I think I am ready” and linking to a video showing him walk into a studio.

Timberlake, a six-time Grammy winner and former member of boy band N’Sync, took a break from music after his 2006 album “Futuresex/Lovesounds” and worked as an actor in movies such as “The Social Network.”

He said in an open letter on his website that the new album is titled “The 20/20 Experience” but gave no further details.

(Reporting by Piya Sinha-Roy; Editing by Jon Boyle)

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Recipes for Health: Skillet Beet and Farro Salad

“Comforting” isn’t a word I usually associate with salads, but this week I put together five grain salads that fit that bill. Over the years I have developed a number of delicious whole grain salads that combine various grains with vegetables, herbs and often nuts, tossed in a tangy dressing. I have also married many a grain and vegetable in a pilaf. I decided to bring both concepts together in hearty salads that I’m calling “skillet salads;” each one is heated through in a skillet just before serving.

You can get ahead on all of these by cooking the grains or noodles ahead. Whole grains freeze well and keep in the refrigerator for three days. Then it’s just a question of preparing vegetables, herbs and dressing. Even if you don’t cook the grains ahead you can prepare the other ingredients while they’re simmering.

I make a meal of these at lunch, and serve smaller portions as sides or starters for dinner. If you want to serve the warm, tangy grains on a bed of salad greens I recommend spinach or sturdy greens like frisée or dandelion greens that will stand up to the heat of the salad and won’t wilt beyond recognition when topped with something warm.

Skillet Beet and Farro Salad

This hearty winter salad can be a meal or a side dish, and warming it in the skillet makes it particularly comforting. Cook your farro until you see that the grains have begun to splay so they won’t be too chewy and can absorb the dressing properly.

For the Salad:

2 medium or 3 small beets, roasted

1 cup farro, soaked for 1 hour in 1 quart water

Salt to taste

1 ounce lightly toasted pistachios (scant 1/4 cup)

1/4 cup chopped fresh herbs, such as parsley, tarragon, marjoram, chives, mint

Freshly ground pepper

For the Dressing:

2 tablespoons sherry vinegar

1 teaspoon balsamic vinegar

Salt to taste

1 small garlic clove, minced or pureéd

1 teaspoon Dijon mustard

1/3 cup extra virgin olive oil

2 tablespoons walnut oil

Crumbled feta for garnish (optional)

1. Roast the beets and meanwhile cook the farro. Place in a medium saucepan with the soaking water and bring to a boil. Add salt to taste, reduce the heat, cover and simmer 45 minutes to an hour, until the grains have begun to splay. Turn off the heat and allow to sit for 15 minutes or longer in the water. Drain through a strainer set over a bowl.

2. While the farro is cooking, make the vinaigrette. Whisk together the vinegars, salt, garlic, and mustard. Whisk in the oils. Pour into a wide frying pan or saucepan and add to the farro, along with a couple of tablespoons of the farro cooking water. Peel and dice the beets and add, along with the herbs and pistachios. Stir over medium heat until heated through and serve, with a little feta sprinkled over the top if you wish.

Yield: Serves 6

Advance preparation: The cooked farro and the roasted beats will keep for 3 or 4 days in the refrigerator.

Nutritional information per serving (6 servings): 304 calories; 19 grams fat; 2 grams saturated fat; 5 grams polyunsaturated fat; 11 grams monounsaturated fat; 0 milligrams cholesterol; 27 grams carbohydrates; 3 grams dietary fiber; 61 milligrams sodium (does not include salt to taste); 6 grams protein

Note: If you want to reduce the fat and calories in this dish, substitute buttermilk for some of the oil. Be careful not to allow the dressing to come to a boil when you heat it in the pan or the buttermilk will curdle.

Martha Rose Shulman is the author of “The Very Best of Recipes for Health.”

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DealBook: With U.P.S. Deal, European Antitrust Regulators Block Another Big Merger

European antitrust regulators proved again on Monday that they were more than willing to flex their considerable muscle.

U.P.S.‘s $6.9 billion bid for TNT Express is the latest merger blocked by the European Union, and certainly the most prominent since the proposed tie-up of NYSE Euronext and Deutsche Börse last year. In the case of U.P.S., European regulators argued that proposed asset sales, including airline operations, would not be enough to appease their concerns over the state of competitiveness in package delivery.

“We are extremely disappointed with the European Commission’s position,” the chief executive of U.P.S., D. Scott Davis, said in a statement. “We proposed significant and tangible remedies designed to address the European Commission’s concerns with the transaction.”

Other antitrust regulators have blocked mergers on antitrust grounds. For example, the Justice Department opposed AT&T‘s proposed $39 billion bid for T-Mobile USA.

But the European Commission, led by Joaquín Almunia, has displayed an aggressive approach that has rankled some deal makers.

Mr. Almunia has acknowledged those concerns, even as he has sought to rebut them. In a speech delivered in November, the commissioner argued that he was not trying to prevent European companies from growing. But he said he was trying to preserve a competitive market place.

“It is simply not true that the commission is putting the brakes on the legitimate efforts of Europe’s firms to scale up,” he said. “What we must avoid are attempts to shield Europe’s companies from competition, in particular during this harsh period for the economy. In this game, only a few of them will benefit, and the majority will lose.”

Among Mr. Almunia’s arguments was that the European Commission was less concerned about high levels of market share than what mergers might do to prices.

In the case of the NYSE Euronext merger, regulators demanded that the two exchange operators sell off significant parts of their businesses. Chief among the European Union’s concerns were the strong position that the two companies would have in the market for derivatives traded on exchanges, leading to a call for the sale of either NYSE Euronext’s Liffe platform or Deutsche Börse’s Eurex unit.

Both companies protested, arguing that the European Union’s view of the market was too limited and did not take into account the broader market for derivatives traded off exchanges. The market operators eventually decided to call off their deal, believing that there was little hope for reversing regulators’ opinion.

Other deals have passed review, but some have required significant changes. In approving Universal Music Group’s takeover of EMI Music last year, for example, European regulators required the sale of a third of EMI’s assets. The decision has led to the auction of music labels like Parlaphone, the home to groups like Coldplay and David Guetta.

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